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Safety in Lactation: Control of epilepsy

21 September 2020Choice will depend on clinical condition, and should primarily be based on suitability for the patient, rather than safety during breastfeeding. Whilst sodium valproate  is…
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Medicine Compliance Aid Stability

genericNon-proprietary

Non-proprietary
generic
Tablets 25mg, 50mg, 100mg, 200mg
R2 · Red 2Drug is not suitable for CAs due to theoretical reasons that cannot be mitigated.
Unsuitable
Original pack contains a dessicant because topirimate is hygroscopic so unsuitable for MCA.
2 March 2015

TopamaxPfizer Ltd

Pfizer Ltd
Topamax
Tablets f/c 25mg, 50mg, 100mg, 200mg
R2 · Red 2Drug is not suitable for CAs due to theoretical reasons that cannot be mitigated.
Unsuitable
Original pack contains a dessicant because topirimate is hygroscopic so unsuitable for MCA.
2 March 2015

Topamax (Sprinkle)Pfizer Ltd

Pfizer Ltd
Topamax (Sprinkle)
Capsules 15mg, 25mg, 50mg
R2 · Red 2Drug is not suitable for CAs due to theoretical reasons that cannot be mitigated.
Unsuitable
Unsuitable for MCA as hygroscopic.
2 March 2015

Lactation Safety Information

For epilepsy

For epilepsy
Suitable alternative antiepileptic
Long half-life increases risk of accumulation in breastfed infants
Limited information indicates that maternal doses of up to 200 mg daily produce relatively low levels in infant serum
Case report of diarrhoea in breast fed infant
31 July 2020