Safety in Lactation: Acne and rosacea

30 October 2020Topical preparations for acne are considered to pose a negligible risk to a breastfeeding infant as long as precautions are taken to avoid contact of…

What issues should be considered in patients with peanut allergy requiring a medicine containing soya?

16 October 2020Peanut and soya belong to the same plant family, so there is concern about cross-sensitivity. This Medicines Q&A (updated April 2020) discusses the issues to…

Safety in Lactation: Other antineoplastic drugs

23 September 2020Antineoplastic agents, whether used as monotherapy or in combination with other antineoplastics, are contra-indicated in breastfeeding (unless indicated below) because of their effects on dividing…

What is the most suitable treatment for acne in a person with acute porphyria?

10 January 2020Topical (applied to the skin) treatments for acne are considered to be safer than oral treatments in people with an acute form of porphyria, provided…
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Lactation Safety Information


No published evidence of safety
Serious adverse effects reported in adults including signs of vitamin D overdose (hypervitaminosis A syndrome)
31 July 2020


Other topical acne preparations
There are no additional risks when used in combination topical preparations containing antimicrobials (erythromycin or clindamycin)
Minimal systemic absorption by mother - see summary
31 July 2020