Valproic acid

Articles · Medicine Compliance Aid Stability · Lactation Safety Information ·


Medicine Compliance Aid Stability

Depakote · Sanofi

Tablets e/c 250mg, 500mg
A3 · Amber 3 · No stability data is available. There are theoretical concerns with use in CAs, which may be mitigated by risk minimisation.
Protect from moisture
Protect from moisture. Max 7 days in MCA.
1st October 2015

Convulex · Pharmacia Ltd

Pharmacia Ltd
Capsules e/c 150mg, 300mg, 500mg
R2 · Red 2 · Drug is not suitable for CAs due to theoretical reasons that cannot be mitigated.
Unsuitable for MCA as preparations are hygroscopic which can affect release profile.
2nd March 2015

Lactation Safety Information

For mania

For mania
Carbamazepine; Appropriate second generation antipsychotic
Significant published evidence of safety in breastfeeding indicates small amounts in breast milk
Monitor infant for jaundice, bruising, and bleeding
MHRA states that it should not used in women of child bearing age unless Pregnancy Prevention Programme is in place, and only if other treatments are ineffective or not tolerated. For this reason, carbamazepine is preferred first-line in breastfeeding (see summary)
22nd January 2020