dm+d

Unassigned

New Medicines

Tenosynovial giant cell tumour

Information

New molecular entity
Deciphera
Deciphera

Development and Regulatory status

Phase III Clinical Trials
Phase III Clinical Trials
Phase III Clinical Trials
Yes

Category

CSF1R kinase inhibitor
Tenosynovial giant cell tumour, historically known as pigmented villonodular synovitis (PVNS), is a rare benign proliferative and inflammatory disease arising from synovia of joints, bursae, or tendon sheaths. Based on a 2017 Dutch study, the global incidence has been estimated to be 43 cases of TGCT per 1 million people in the general population. For localised TGCT, 39 cases per 1 million are estimated, whereas for diffuse TGCT, 4 cases per 1 million are estimated [3,4].
Tenosynovial giant cell tumour
Oral