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Articles
Vincristine: Cytotoxic Drug Stability Monograph
15 December 2020Stability information is essential for the safe aseptic preparation of vincristine
Safety in Lactation: Vinca alkaloids and etoposide
21 September 2020Vinca alkaloids, whether used as monotherapy or in combination with other antineoplastics, are contra-indicated in breastfeeding because of their cytotoxic action on dividing cells and…
Refrigerated Storage
Vincristine sulphateHospira UK Ltd (part of Pfizer)
Hospira UK Ltd (part of Pfizer)
Vincristine sulphate
Injection (1mg/ml)
In the event of an inadvertent temperature excursion the following data may be used:
In-house data from the manufacturer indicate that vincristine is stable when exposed to temperatures of up to 25°C or -20°C for up to one month.
Contact Pfizer in cases where additional stability data is required. Refer to the electronic medicines compendium (eMC) at medicines.org.uk for company contact details.
29 December 2021
London MI Service
Lactation Safety Information
No published evidence of safety
Serious adverse effects reported in adults
5 March 2020