dm+d

108792008

Articles

Vinorelbine: Cytotoxic Drug Stability Monograph

15 December 2020Stability information is essential for the safe aseptic preparation of vinorelbine

Safety in Lactation: Vinca alkaloids and etoposide

21 September 2020Vinca alkaloids, whether used as monotherapy or in combination with other antineoplastics, are contra-indicated in breastfeeding because of their cytotoxic action on dividing cells and…
Search Articles

Refrigerated Storage

NavelbinePierre Fabre

Pierre Fabre
Navelbine
10mg/mL concentrate for solution for infusion

Stability Data In the event of an inadvertent temperature excursion the following data may be used:
Navelbine concentrate for solution for infusion can remain for a maximum of 48 hours in total for the same batch number between 8⁰C and 32⁰C without any deterioration of the product or alteration to the expiry date.

Each unit (packaging) having suffered a temperature excursion should be marked and tracked to ensure that any potential further exposure to temperature excursions does not exceed 48 hours in total for the same batch number.
Please also refer to the manufacturer’s product literature for recommended storage information at https://www.medicines.org.uk

No
Yes
28 September 2020
London Medicines Information Service

NavelbinePierre Fabre

Pierre Fabre
Navelbine
Soft capsules, 20mg, 30mg and 80mg

In the event of an inadvertent temperature excursion the following data may be used:
Navelbine soft capsules can remain for a maximum of 48 hours in total for the same batch number between 8⁰C and 32⁰C without any deterioration of the product or alteration to the expiry date.

Each unit (packaging) having suffered a temperature excursion should be marked and tracked to ensure that any potential further exposure to temperature excursions does not exceed 48 hours in total for the same batch number.

Please also refer to the manufacturer’s product literature for recommended storage information at https://www.medicines.org.uk

No
Yes
28 September 2020
London Medicines Information Service

Lactation Safety Information

No
No published evidence of safety
Serious adverse effects reported in adults
11 September 2020