dm+d

Unassigned

New Medicines

Major depressive disorder in adults

Information

New molecular entity
Biogen
SAGE Therapeutics

Development and Regulatory status

None
None
Phase III Clinical Trials

Category

Selective positive allosteric modulator of GABAA receptors
Annually, 5% of adults have an episode of depression. About one in four women and one in ten men will develop depression severe enough to require treatment at some time in their lives. Most depressive states are at the mild-to-moderate end of the spectrum and it is these that are mainly seen in primary care [1].
Major depressive disorder in adults
Oral

Post-partum depressive disorder

Information

New molecular entity
Biogen
SAGE Therapeutics

Development and Regulatory status

None
None
Phase III Clinical Trials

Category

Selective positive allosteric modulator of GABAA receptors
Postpartum depression is estimated to occur in 10 to 15% of mothers in the developed world [2].
Post-partum depressive disorder
Oral