Safety in Lactation: Alkylating drugs

Alkylating agents, whether used as monotherapy or in combination with other antineoplastics, are contra-indicated in breastfeeding because of their cytotoxic action on dividing cells and…

Safety in Lactation: Antifungal drugs

There is very limited information on the use of antifungals during breastfeeding. Fluconazole is the preferred antifungal, if clinically indicated. Monitor infant for gastro-intestinal disturbances,…

Safety in Lactation: Antigiardial drugs

Mepacrine can either be used short-term for giardiasis infections or long-term for discoid lupus erythematosus. There is no information regarding its use during breastfeeding. Suitable…

Safety in Lactation: Antileprotic drugs

A clinical decision regarding whether a mother with leprosy should breastfeed needs to be made initially. By providing the information regarding the safety of antileprotic…

Safety in Lactation: Antimigraine drugs

If simple analgesics, e.g. paracetamol and ibuprofen, are insufficient to treat symptoms, sumatriptan is the drug of choice for the treatment of acute migraine. Although…

Safety in Lactation: Antimuscarinic drugs

These antimuscarinics are used as premedication, to dry secretions, and for intraoperative bradycardia. They are given as a single dose by injection, repeated if necessary…

Safety in Lactation: Antithyroid drugs

For use of carbimazole or propylthiouracil, monitoring the infant’s thyroid function should be considered, especially in newborn infants, although no cases of thyroid function alteration…

Safety in Lactation: Antituberculosis drugs

The US Centers for Disease Control and Prevention and other professional organisations advise that breastfeeding should not be discouraged in women with tuberculosis. However, the…
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