Safety in Lactation: Opioid analgesics

Can opioids be used for pain relief during pregnancy?

What naloxone doses should be used in adults to urgently reverse the effects of opioids?

The opioid antagonist, naloxone, is a highly effective antidote the use of which is potentially life-saving. The drug has a role in a wide range…

In use product safety assessment report: Onexila® XL (oxycodone once daily prolonged release tablets)

A UKMi Product Safety assessment on Onexila® XL (oxycodone once daily prolonged release tablets); in-use medication safety considerations resultant from the product presentation or other…

What is serotonin syndrome and which medicines cause it?

This Medicines Q&A outlines the causes and symptoms of serotonin syndrome and lists examples of medicines with the potential to cause serotonin syndrome

What are the equivalent doses of oral morphine to other oral opioids when used as analgesics in adult palliative care?

Morphine is generally the strong opioid of choice for treating moderate to severe cancer pain and a common question is how to convert a dose…