It is important to complete an individual risk assessment for your patient and to apply the principles of prescribing during pregnancy when looking at the available information and making treatment decisions. Check to see if a risk assessment has already been completed by the specialist team.
Untreated or inadequately treated severe or chronic pain, can have adverse effects on the mother and therefore on the foetus.
There are no specific guidelines for the management of pain in pregnancy. You should check to see if there is local guidance for you to use in your area.
Not all analgesics recommended in commonly used pain ladders are suitable for use during, or at certain stages of, pregnancy.
Non-pharmacological measures should be tried whenever appropriate or possible, before a medicine is considered.
Choice of analgesic should largely be guided by treatment recommendations for the same type or severity of pain in non-pregnant patients, but will need to take possible risks to the foetus into account.
- Physiotherapy, hot and cold packs, TENS, and pain management programmes
If non-pharmacological measures are ineffective, unsuitable or symptoms do not respond adequately, oral analgesia may be considered.
- Paracetamol is the analgesia of choice for mild to moderate pain and pyrexia.
- Weak opioid codeine may be used where paracetamol has not been effective.
- NSAID (ibuprofen preferred), may be used if needed for inflammatory pain in first and second trimester. NSAIDs should not be given after week 28, unless unavoidable and with appropriate monitoring in place.
- Use of any opioid during pregnancy, particularly around the time of delivery risks neonatal respiratory depression.
- Prolonged use of opioids throughout pregnancy may result in neonatal withdrawal.
SPS provides more detailed information on what opioids can be used for pain relief during pregnancy
Pregnancy outcome information
UK Teratology Information Service (UKTIS) provides an overview on pain management in pregnancy including neuropathic pain; and more detailed information on pregnancy outcomes for many common analgesics including paracetamol, codeine or dihydrocodeine, NSAIDs, ibuprofen, tramadol and morphine.
Each of the UKTIS summaries has corresponding Best Use of Medicines in Pregnancy (BUMPS) patient information.
NHS Medicines A-Z provides a summary statement on the use in pregnancy of specific analgesics.