Dosing

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Dosing information for AstraZeneca COVID-19 Vaccine

13 January 2021Information on intervals between dosing and completion of the vaccination schedule with an alternative brand of vaccine is given.

Dosing information for Pfizer-BioNTech COVID-19 Vaccine

7 January 2021Information on intervals between dosing and completion of the vaccination schedule where an alternative brand of vaccine is given.

Equivalent doses of oral benzodiazepines

8 December 2020Benzodiazepines are the most commonly used anxiolytics and hypnotics. There are major differences in potency between different benzodiazepines and this difference in potency is important…

Can low dose aspirin be used in breastfeeding mothers as an antiplatelet agent?

29 October 2020Limited data and pharmacokinetics indicate that low dose aspirin (defined here as 75 – 150mg daily) passes into breast milk in small amounts.   There…

What is the optimal prokinetic dose of erythromycin in adults?

22 October 2020This updated Medicines Q&A evaluates the available evidence for the use of erythromycin as a prokinetic agent in adults Summary The ideal prokinetic dose of…

Should patients drink alcohol whilst taking long-term low-dose methotrexate?

22 September 2020This Medicines Q&A reviews the evidence that alcohol increases risk of methotrexate-induced liver toxicity, and advises on safe levels of alcohol intake by patients taking…

Can a PGD be used to adjust doses of a patient’s medication?

9 September 2020No – a PGD does not give a legal framework for healthcare professionals to adjust a dose of medicine already in a patient’s possession and…

Is it acceptable to have a dose range specified in a Patient Group Direction (PGD) rather than a specified dose?

9 September 2020Yes this is acceptable. The legislation requires that the applicable dose or maximum dose is specified. The PGD may therefore specify a single dose or…

MUS Webinar – Update on NICE VTE Management Guidance & Safer Use of Anticoagulation in Primary Care

14 October 2020In this webinar, Frances and Alison outlined important issues from World Thrombosis week and key points from the NICE VTE guidelines (NG158, March 2020) and…

NPSA Rapid Response Report RRR018 -Preventing fatalities from medication loading doses. A UKMi risk assessment tool to support local implementation

17 August 2020The NPSA rapid response report on preventing fatalities from medication loading doses directs organisations to identify and risk assess use of loading doses with the…