Renal and urologic disorders, Guidance

Does horny goat weed have any clinically significant interactions?

3 May 2020Horny goat weed (Epimedium) is a herbal medicine that may comprise of mixtures of different related Epimedium species, which contain numerous and varied active constituents. …

Drugs for urinary disorders – are any lactose-free?

5 February 2020This Medicine Q&A gives details of available urinary frequency, enuresis, incontinence and urinary retention preparations that do not contain lactose. There is a lactose-free preparation…

Shortage of Mitomycin-C Kyowa (all strengths)

7 November 2019UKMi with input from the Royal College of Ophthalmology and the National Clinical Director for Cancer at NHS England and Improvement, has drafted clinical advice…

Low molecular weight heparins – should prophylactic doses be used in patients with renal impairment?

23 October 2019This updated Medicines Q & A reviews the evidence available and considers when prophylactic doses of low molecular weight heparins can be used in patients…

Methotrexate dosing in renal impairment – more awareness and action needed

15 April 2019Chronic kidney disease impacts upon prescribing for some disease modifying anti-rheumatic drugs. Methotrexate is usually hospital-initiated but rheumatology and dermatology patients will be monitored by…

Which estimate of renal function should be used when dosing patients with renal impairment?

26 February 2018**THIS DOCUMENT IS UNDER REVIEW** Accurate measurement of renal function is essential in patients with renal impairment (RI) so that drug dosages can be adjusted…

What factors need to be considered when dosing patients with renal impairment?

15 January 2018** THIS DOCUMENT IS UNDER REVIEW** Many commonly used drugs or their metabolites are excreted by the kidney, and this has particular significance for people…

What factors need to be considered when dosing patients on renal replacement therapies?

20 June 2017**THIS DOCUMENT IS UNDER REVIEW** There are a number of inter-dependent factors that need to be considered when dosing patients on RRT. Consider the drug,…