Neurological disorders, Guidance

Shortage of clonidine 25microgram tablets

14 July 2020Accord are out of stock and unable to advise on a resupply date. Sandoz are out of stock but expect to have further supplies week…

Shortage of Ativan (lorazepam) Injection 4 mg in 1 ml

27 April 2020Supplies will be extremely limited between week commencing 5th October until early December 2020 and reserved for primary care only. Pfizer is supplying an alternative…

Shortage of Diazemuls (diazepam 5mg/ml emulsion for injection)

16 March 2020Accord (sole supplier) is out of stock. Importers are unable to source unlicensed supplies. This memo discusses alternative treatment options.

What is the evidence for low dose naltrexone for treatment of multiple sclerosis?

11 February 2020This updated Medicines Q&A evaluates the limited evidence available for low dose naltrexone for treatment of multiple sclerosis.  

Can riboflavin reduce the incidence of migraines in adults?

9 December 2019This updated Medicines Q&A evaluates the limited evidence available on the effectiveness of riboflavin for the prevention of migraine in adults. UK guidelines for the…

Shortage of metoprolol 50mg and 100mg tablets

22 February 2019There are intermittent supply issues as some manufacturers have recently discontinued these products and others are having supply difficulties. Supplies of both strengths are currently…

Safety in Lactation: Drugs for movement disorders

10 November 2018Additional information relating to breastfeeding To be used in conjunction with individual drug entries for specific information and guidance.  Drugs for dystonias and other involuntary…

Hypersalivation – what are the treatment alternatives to glycopyrronium and hyoscine?

1 August 2018This Medicines Q&A outlines possible alternatives to hyoscine hydrobromide and glycopyrronium in the treatment of non drug-induced hypersalivation, e.g. botulinum toxin, amitriptyline, atropine (eye drops…

Drug-induced hypersalivation – what treatment options are available?

1 August 2018This Medicines Q&A summarises published studies or case reports concerning the pharmacological treatment of drug-induced hypersalivation (drooling or sialorrhoea), particularly hypersalivation caused by clozapine. Update…

Ofatumumab

3 February 2016dm+d: 444609007