Clonidine products vary in their licensed status and other characteristics which affects their suitability for intrathecal administration

Licensed for intrathecal use

Products licensed for intrathecal use are the first line option and should be used wherever suitable.

There are currently no known clonidine products licensed for intrathecal administration.

Not licensed for intrathecal use, limited information available

Products with partial information that are not licensed for intrathecal administration can still sometimes be used. Refer to the advice in our article and complete a risk assessment to enable you to interpret the details below and choose an appropriate product.

Glenwood (Catapres®)


150 micrograms in 1mL ampoule


Sodium chloride, 1N hydrochloric acid, water for injection


237 – 301 mOsmol/kg (undiluted)


4 – 6 (undiluted)

Endotoxin content

No information

Unlicensed ‘Special’, specified for intrathecal use

Unlicensed medicines that are manufactured in MHRA-licensed Specials Manufacturing Units, at the request of an authorised healthcare professional specifically for intrathecal use.

St Mary’s Pharmaceutical Unit, Cardiff


2mg/mL in 10mL vials

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