Infection and infectious diseases, Guidance

Metronidazole – is it safe to use with breastfeeding?

12 October 2020The balance of current evidence and clinical experience, and the consensus of specialist opinion, is that there is no established mutagenic or carcinogenic risk to…

Oseltamivir or zanamivir – can they be used in breastfeeding mothers for the treatment or prophylaxis of influenza?

7 August 2020This updated Medicines Q&A evaluates the available evidence for oseltamivir and zanamivir when used in breastfeeding mothers for the treatment or prophylaxis of influenza. In…

Shortage of isoniazid tablets 50mg

24 June 2020There is a shortage of this strength of isoniazid tablets until late July 2020. Stock of 100mg isoniazid tablets are available to bridge the gap.…

Change of maternal pertussis vaccine

29 January 2020The maternal pertussis immunisation programme commenced in October 2012, initially using Repevax® vaccine (dTaP/IPV). From July 2014, Boostrix®-IPV (dTaP/IPV) has been supplied. From mid-January 2020,…

Do NSAIDs increase the risk of severe skin reactions in children with chickenpox?

1 October 2019This Q&A evaluates the limited published evidence investigating an association between Non-steroidal anti-inflammatory drugs (NSAIDs) and severe skin reactions in children with chickenpox.

Chloramphenicol: is it safe in breastfeeding?

15 March 2019This updated Medicines Q&A discusses the safety of the antibiotic, chloramphenicol (systemic and ophthalmic), in breastfeeding women.

Safety in Lactation: Non-beta lactam antibiotics and antibacterials

20 August 2018paedAdditional information relating to breastfeeding To be used in conjunction with individual drug entries for specific information and guidance. Aminoglycosides Only small or negligible amounts…

Guidance on the Pharmaceutical Issues concerning Outpatient Parenteral Antibiotic Therapy (OPAT) and other Outpatient IV Therapy Services 1st Edition January 2018

30 July 2018The development of OPAT (Outpatient Parenteral Antibiotic Therapy) services and other outpatient intravenous therapies has been rapid over recent years and there are many models…