Is there a role for inhaled epoprostenol, inhaled nitric oxide or sildenafil to treat secondary pulmonary hypertension and hypoxaemia in ICU patients with acute respiratory distress syndrome?

An analysis of pooled randomised controlled trials of the use of inhaled nitric oxide in patients with acute respiratory distress syndrome (ARDS) found no mortality…

Low molecular weight heparins - should treatment doses be used in patients with renal impairment?

Randomised controlled trials evaluating LMWH efficacy and safety have generally excluded patients with severe renal impairment (RI). In contrast to UFH, LMWHs are primarily cleared…

Summary of COVID-19 medicines guidance: Respiratory disorders

This page summarises and signposts to medicine related guidance we’re aware of from professional and government bodies relating to coronavirus and respiratory disorders. This page…

Administration of tobramycin via a nebuliser

If there are robust clinical reasons to administer tobramycin injection via a nebuliser instead of using the licensed nebuliser solution then it is critical that…

Ethanol content of inhalers – What is the significance?

Ethanol is included as an excipient in many commonly prescribed inhalers, including some licensed for use in children.  Patients may have ethical, religious or cultural…

NICE Bites - Pneumonia

Please go to NICE to check for any recent updates to this guideline. NICE Bites is a monthly prescribing bulletin published by North West Medicines…