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COVID-19 Treatments

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Using nirmatrelvir and ritonavir (Paxlovid) in practice

30 June 2023Support for prescribing decisions in people on interacting medicines, those with swallowing difficulties, renal impairment, or who are pregnant or breastfeeding

Managing risk when supplying and administering COVID-19 treatments across the system

20 December 2021Differing models exist for the supply and administration of COVID-19 treatments. We guide through the risks and mitigations associated with each.

Nirmatrelvir + ritonavir (Paxlovid)

Using COVID-19 treatments in practice

15 December 2021Deployment should address a range of factors and be implemented through different mechanisms. Collecting data and learning will support continued safe use.

Handling and preparation of sotrovimab

14 December 2021An outline process and supporting materials to help Trusts deploy sotrovimab

Using Tocilizumab for hospitalised patients with COVID-19 who are pregnant

12 October 2021A careful risk assessment should be done on the benefits of this off-label use to the mother, and the risks it poses to the fetus or neonate.

Using Tocilizumab or Sarilumab for hospitalised patients with COVID-19 who are breastfeeding

12 October 2021Tocilizumab and sarilumab can be used off-label to treat hospitalised patients with COVID-19. Breastfeeding can continue if these treatments are required.