14 October 2022 · Constipation in people taking clozapine can be fatal. Guidance on preventing and managing constipation in these individuals is described.
31 May 2023 · Guidance on clozapine administration including crushing tablets, importance of not missing doses and practical considerations regarding switching formulations
28 June 2024 · Healthcare professionals in all settings who interact with patients prescribed clozapine should be aware of clinical considerations related to its use.
28 June 2024 · Healthcare professionals in non-specialist services managing patients prescribed clozapine should implement safe practice principles to prevent potential harms.
14 July 2025 · Quetiapine is the preferred second-generation, and haloperidol the preferred first-generation antipsychotic when breastfeeding full term, healthy infants.