Paracetamol

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Safety in Lactation: Simple analgesics and combination analgesic preparations

26 October 2020Paracetamol is the simple analgesic of choice in breastfeeding mothers. Choice of an alternative will depend on level of analgesia required. Paracetamol should be adequate…

Can breastfeeding mothers take paracetamol or paracetamol combination products?

3 June 2020This updated Medicines Q&A evaluates the available evidence for the safety of paracetamol in breastfeeding mothers. The updated version also contains information on paracetamol combination…

How should medicines be dosed in children who are obese?

18 October 2018Obesity results in physiological changes that can affect the volume of distribution and the clearance of drugs. The extent of these changes is variable and…

In use product safety assessment report for intravenous paracetamol in paediatrics

17 July 2018In May 2010, the Medicines and Healthcare products Regulatory Agency (MHRA) issued a safety update to healthcare professionals in the UK highlighting the risk of…

What advice should be given to people with porphyria who are undergoing dental procedures?

17 March 2017An indication of the safety of various medicines commonly used by dentists in patients with acute porphyria is given. When considering the safety of medicines…

ARCHIVED NPSA Signal – Overdose of intravenous paracetamol in infants and children – October 2010

29 October 2010  Key risks emerging from the review of serious incidents reported by the NHS to its National Reporting and Learning System (NRLS) were shared in…

ARCHIVED NPSA Signal – Detecting harm following paracetamol overdose – October 2010

29 October 2010Key risks emerging from the review of serious incidents reported by the NHS to its National Reporting and Learning System (NRLS) were shared in in…