Preparation of injectable medicines in clinical areas: quick reference guides

Occasionally staff may need to prepare unfamiliar injectable medicines at the patient’s bedside. These cards have been produced and validated by SPS quality assurance professionals.The…

What naloxone doses should be used in adults to urgently reverse the effects of opioids?

The opioid antagonist, naloxone, is a highly effective antidote the use of which is potentially life-saving. The drug has a role in a wide range…

National Ambulance Patient Group Directions

National PGDs National PGDs have been developed for ambulance services commissioned by NHS England.  They are supported by NASMeD and JRCALC. Organisations need to adopt them…

Patient Group Directions for Chemical, Biological, Radiological and Nuclear (CBRN) incidents

A specific set of PGDs have been developed by Public Health England (PHE) in partnership with NHS England, the Department of Health and Social Care…

Regional Medicines Optimisation Committee Antidotes and RUMs Position Statement

Attached is the final position statement produced by the London RMOC on access to and availability of antidotes and rarely used medicines (RUMs) published in…

Shortage of Diazemuls (diazepam 5mg/ml emulsion for injection)

Accord (sole supplier) is out of stock. Importers are unable to source unlicensed supplies. This memo discusses alternative treatment options.

In use product safety assessment report: naloxone products for emergency opiate reversal in non-medical settings

A UKMi Product Safety assessment on naloxone products for emergency opiate reversal in non-medical settings; in-use medication safety considerations resultant from the product presentation or…

LMEN: Summary of antidotes to NOACs (including those currently in development) which could impact NOAC use in the future

NOACs offer convenient fixed dosing without need for routine coagulation monitoring and they have predictable pharmacokinetics, fewer interactions and quicker onset (and offset) of action…