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Operational Implications of UK Exit from the EU for NHS Clinical Trial Sites

16 September 2022A summary of the implications of the UKs exit from the EU for clinical trial sites for both IMP and ATIMPs, including supply to and from Northern Ireland

Prescribing available HRT products

28 April 2022Hormone Replacement Therapy availability varies currently. Check for available products and keep up-to-date. Supply content is maintained regularly by DHSC.

Labelling and packaging of unlicensed medicines (Specials): best practice guidance for the NHS

1 March 2022National guidance from NHSE/I to reduce LASA errors and improve patient safety when considering requirements for unlicensed specials medicines

Legal mechanisms to supply and administer medicines to individuals

24 January 2022The main legal mechanisms used to supply and/or administer medicines are explained and considerations suggested for the most appropriate option(s)

Supply and/or administration of Controlled Drugs under a PGD

16 November 2021The legal position on the supply and/or administration of controlled drugs under Patient Group Directions is summarised

Unlicensed medicines and use of PGDs

16 November 2021This page explains why PGDs are not a legal mechanism for the administration or supply of unlicensed medicines.

Understanding why PGDs cannot be used for dose adjustments

16 November 2021This article outlines why PGDs cannot be used to adjust the dosage of a medicine already in an individual's possession.

Off label medicine use under a Patient Group Direction

10 June 2021This article explains the legislation and guidance on the use of PGDs when a medicine is to be used outside its licence ('off-label').

Including medicines with Risk Minimisation Measures (RMM) in PGDs

16 March 2021Medicines with RMM may not be suitable for inclusion within Patient Group Directions (PGDs). If used, the RMM must be stated within the PGD.

Patient Group Directions (PGDs) and abortifacients

14 September 2020This article advises on the legal position on the supply/administration of abortifacients under PGDs.