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Mental health and illness

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Clozapine use in adults with swallowing difficulties

31 May 2023Guidance on clozapine administration including crushing tablets, importance of not missing doses and practical considerations regarding switching formulations

Choosing equivalent doses of oral benzodiazepines

25 January 2022Approximate equivalent doses of oral benzodiazepines to diazepam. Doses are not exact because of differences between the medicines.

Choosing an antidepressant for people with coronary heart disease

29 April 2025Sertraline is the first-line option in people with coronary heart disease. Alternatives include fluoxetine, paroxetine and mirtazapine.

Agomelatine to other antidepressants: switching in adults

17 February 2023Suggested methods for switching safely from agomelatine to other antidepressants. Switches requiring additional specialist support are highlighted.