17 February 2023 · Prior response, side-effects, new contraindications, and current depression symptoms may require switching antidepressants. When it is, establish shared goals.
31 May 2023 · Guidance on clozapine administration including crushing tablets, importance of not missing doses and practical considerations regarding switching formulations
14 October 2022 · Constipation in people taking clozapine can be fatal. Guidance on preventing and managing constipation in these individuals is described.
29 April 2025 · Sertraline is the first-line option in people with coronary heart disease. Alternatives include fluoxetine, paroxetine and mirtazapine.
1 August 2023 · Methadone is the preferred choice of treatment for opioid dependence during breastfeeding. Recommendations apply to full term and healthy infants only.
15 November 2023 · Duloxetine, mirtazapine, trazodone or venlafaxine can be used with caution but other options are preferred. Recommendations apply to full term, healthy infants.
3 February 2023 · Suggested resources to help primary care healthcare professionals find information on psychotropic and other medicines used in psychiatry
17 February 2023 · Suggested methods for switching safely between SSRIs or to other antidepressants. Switches requiring additional specialist support are highlighted.
17 February 2023 · Suggested methods for switching safely from vortioxetine to other antidepressants. Switches requiring additional specialist support are highlighted.