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Aseptic services

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Phenol: informing intrathecal risk assessment

11 August 2022Phenol products vary in their licensed status and other characteristics which affects their suitability for intrathecal administration

Morphine: informing intrathecal risk assessment

11 August 2022Morphine sulfate products vary in their licensed status and other characteristics which affects their suitability for intrathecal administration

Microbiological Protocol for the Integrity Testing of Syringes, 2nd Edition, April 2013 (Yellow Cover)

29 July 2013Disposable syringes are regularly used as final containers for aseptic products prepared within hospital units. This protocol is intended to describe standardised and validated methods…

Methotrexate: informing intrathecal risk assessment

11 August 2022Methotrexate products vary in their licensed status and other characteristics which affects their suitability for intrathecal administration

Measurement of HEPA filter performance using the dispersed oil particle aerosol test for leak detection in filter installations ed 3

20 December 2018This test protocol is supplementary to Quality Assurance of Aseptic Preparation Services, Fifth edition, Edited by Alison M Beaney, Pharmaceutical Press, 2016.

Managing defective medicines

19 June 2023An overview of what defective medicines are and how they should be reported by NHS personnel.

Managing an intrathecal chemotherapy service

13 June 2025The intrathecal route is a high-risk route of administration. There are minimum requirements for providing intrathecal chemotherapy.
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Management of Particulate Contamination of Aseptically Prepared Products - NHS Pharmaceutical Quality Assurance Committee Guidance Note

24 November 2020Management of Particulate Contamination of Aseptically Prepared Products – NHS Pharmaceutical Quality Assurance Committee Guidance Note

Making best use of restricted aseptic compounding capacity

18 September 2018The NHS is experiencing considerable challenges regarding the supply of aseptically prepared injectable medicines. This communication from NPSG advises all NHS customers of commercial aseptic…

Lidocaine: informing intrathecal risk assessment

11 August 2022Lidocaine products vary in their licensed status and other characteristics which affects their suitability for intrathecal administration