Leflunomide

Articles · Medicine Compliance Aid Stability · Lactation Safety Information ·
109143003

Articles

Safety in Lactation: Drugs which suppress the rheumatic disease process

Disease-modifying anti-rheumatic drugs (DMARDs) have a varied pharmacology, mainly either modifying the immune response to the disease or modifying the disease process. The choice of… Abatacept Adalimumab Anakinra Azathioprine Belimumab Certolizumab pegol Chloroquine Ciclosporin Etanercept Golimumab Hydroxychloroquine Infliximab Leflunomide Methotrexate Penicillamine Rituximab Sulfasalazine Tocilizumab Ustekinumab

Medicine Compliance Aid Stability

Arava · Sanofi-Aventis

Sanofi-Aventis
Arava
Tablets 10mg, 20mg, 100mg
R2 · Red 2 · Drug is not suitable for CAs due to theoretical reasons that cannot be mitigated.
Unsuitable
Tablets are hygroscopic
11th February 2015

generic · Sandoz Ltd

Sandoz Ltd
generic
Tablets 10mg, 20mg, 100mg
R2 · Red 2 · Drug is not suitable for CAs due to theoretical reasons that cannot be mitigated.
Unsuitable
Tablets are hygroscopic
11th February 2015

generic · Medac Gmbh

Medac Gmbh
generic
Tablets 10mg, 20mg, 100mg
R2 · Red 2 · Drug is not suitable for CAs due to theoretical reasons that cannot be mitigated.
Unsuitable
Tablets are hygroscopic
11th February 2015

generic · Aspire Pharma

Aspire Pharma
generic
Tablets 10mg, 20mg, 100mg
A3 · Amber 3 · No stability data is available. There are theoretical concerns with use in CAs, which may be mitigated by risk minimisation.
Protect from light
Protect from moisture
Manufacturer advice available. Max 7 days in MCA.

generic · Zentiva

Zentiva
generic
Tablets 10mg, 20mg, 100mg
R2 · Red 2 · Drug is not suitable for CAs due to theoretical reasons that cannot be mitigated.
Unsuitable
Tablets are hygroscopic.
11th February 2015

Lactation Safety Information

See summary
Long half-life increases risk of accumulation in breastfed infants
No published evidence of safety
Serious adverse effects reported in adults