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Articles

Aciclovir (oral) for genital HSV infection

5 October 2021SPS PGD template for the supply of aciclovir (oral) to treat genital herpes simplex virus (HSV) infections.

How should medicines be dosed in children who are obese?

28 May 2021Review on how to calculate medicine doses in children who are obese which includes a table on commonly prescribed medicines.

Safety in Lactation: Anti-infective eye preparations

30 October 2020Anti-infective preparations for ophthalmic use have limited systemic absorption in the mother, and pose negligible risk to a breastfed infant. Systemic absorption from eye drops…

Safety in Lactation: Herpes simplex and varicella-zoster infection

21 September 2020Although there is limited evidence for the use of these antivirals during breastfeeding, aciclovir is the preferred choice. Valaciclovir is also an acceptable choice since…
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Lactation Safety Information

Oral / Intravenous

Oral / Intravenous
Yes
Small amounts in breast milk
Used in full-term neonates from birth
Moderate level of evidence of use in breastfeeding
Poor oral bioavailability
17 September 2020

For use in the eye

For use in the eye
Yes
Ganciclovir
No published evidence for use in breastfeeding
Limited systemic absorption in the mother, therefore negligible risk to the infant
14 June 2022

For topical use

For topical use
Yes
No published evidence of safety
Remove product from the breast before feeding (creams are easier to remove than ointments)
14 June 2022