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LMEN: Summary of antidotes to NOACs (including those currently in development) which could impact NOAC use in the future

3 February 2016NOACs offer convenient fixed dosing without need for routine coagulation monitoring and they have predictable pharmacokinetics, fewer interactions and quicker onset (and offset) of action…

What naloxone doses should be used in adults to urgently reverse the effects of opioids?

19 December 2019The opioid antagonist, naloxone, is a highly effective antidote the use of which is potentially life-saving. The drug has a role in a wide range…

Ronopterin

Entolimod

Regional Medicines Optimisation Committee Antidotes and RUMs Position Statement

17 June 2019Attached is the final position statement produced by the London RMOC on access to and availability of antidotes and rarely used medicines (RUMs) published in…

Preparation of injectable medicines in clinical areas: quick reference guides

27 July 2020Occasionally staff may need to prepare unfamiliar injectable medicines at the patient’s bedside. These cards have been produced and validated by SPS quality assurance professionals.…

Administration of diazepam rectal tubes by registered Paramedics and Nurses for the management of seizures: PGD template

5 October 2021A PGD template developed by SPS and supported by NASMeD and JRCALC for ambulance services commissioned by NHS England.

Administration of flumazenil by registered Paramedics or Nurses for the complete or partial reversal of the central sedative effects of midazolam used for conscious sedation: National PGD

5 October 2021A national PGD developed by SPS and supported by NASMeD and JRCALC for ambulance services commissioned by NHS England.

Administration of buccal midazolam by registered Paramedics and Nurses for the management of seizures: PGD template