Gastrointestinal disorders
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Preparing to use golimumab biosimilar
17 October 2025Golimumab biosimilars are expected soon. We offer general information and implementation advice.
Using and prescribing thiamine in alcohol dependence
25 September 2025Intramuscular and intravenous thiamine can be used to prevent complications of alcohol dependence such as Wernicke’s encephalopathy.
Preparing to use ustekinumab biosimilar
29 July 2025Introducing biosimilar ustekinumab needs planning. Work with the multidisciplinary team to ensure familiarity with the area and develop an implementation plan.
Good governance when implementing ustekinumab biosimilar
29 July 2025Governance should consider processes for approval, procurement and supply, prescribing and administration, monitoring, and pharmacovigilance.
The licence and supporting evidence for ustekinumab biosimilars
29 July 2025Ustekinumab biosimilars (Pyzchiva, Steqeyma, Uzpruvo, Wezenla) are licensed. Learn about indications, formulations, supporting evidence and differences.
Considerations for using medicines following bariatric surgery
30 May 2025Guidance on the physiological changes after bariatric surgery that can affect the pharmacokinetics of medicines and supplements.
Prescribing and using thiamine to prevent refeeding syndrome
11 March 2025Intravenous thiamine for prevention of refeeding syndrome should be reserved for those with intestinal failure where the oral or enteral route is unavailable.
Haemorrhoids: treatment during pregnancy
4 March 2025Use non-pharmacological treatment for the management of haemorrhoids during pregnancy. If insufficient use a topical haemorrhoidal preparation.
Using loperamide in high output stoma or short bowel syndrome
7 November 2024This guidance explores the dosing and monitoring advice when using high dose loperamide to reduce high stoma output or in short bowel syndrome in adults.
PPI suggestions for adults with swallowing difficulties
14 June 2024A range of proton pump inhibitor (PPI) formulations are suitable for adults with swallowing difficulties.