Mental health and illness, Guidance
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Using antidepressants for depression in people with epilepsy
21 February 2024Antidepressant use requires special consideration in people with epilepsy. Treating depression in stable epilepsy is covered.
Managing constipation in people taking clozapine
14 October 2022Constipation in people taking clozapine can be fatal. Guidance on preventing and managing constipation in these individuals is described.
Using SSRI antidepressants during breastfeeding
17 November 2023Paroxetine and sertraline are the Selective Serotonin Reuptake Inhibitors (SSRIs) of choice. Recommendations apply to full term and healthy infants only.
Using tricyclic antidepressants during breastfeeding
17 November 2023Imipramine and nortriptyline are the tricyclic antidepressants of choice. Recommendations apply to full term and healthy infants only.
Tricyclics to other antidepressants: switching in adults
31 May 2024Suggested methods for switching safely between tricyclics or to other antidepressants. Switches requiring additional specialist support are highlighted.
SSRIs to other antidepressants: switching in adults
31 May 2024Suggested methods for switching safely between SSRIs or to other antidepressants. Switches requiring additional specialist support are highlighted.
Considerations when choosing an alternative antidepressant
17 September 2024Consider the risks associated with switching an antidepressant for depression, the patient's individual circumstances and when to seek specialist advice.
Establishing if a person needs to switch their antidepressant
28 March 2023Prior response, side-effects, new contraindications, and current depression symptoms may require switching antidepressants. When it is, establish shared goals.
Monitoring a person during and after antidepressant switching
17 September 2024Review people at appropriate time points; advise on what to expect and report; and beware of the possibility of withdrawal symptoms and serotonin syndrome.
Planning and agreeing an antidepressant switching strategy
17 September 2024Guidance on planning and implementing the antidepressant switch after the need and choice of antidepressant have been decided.