Aseptic services

Managing an intrathecal chemotherapy service

13 June 2025The intrathecal route is a high-risk route of administration. There are minimum requirements for providing intrathecal chemotherapy.

Understanding risks with intrathecal administration

13 June 2025The intrathecal route is a high-risk route of administration. Incorrect administration of medicines unsafe for this route can result in patient death.

Ziconotide: informing intrathecal risk assessment

16 May 2025Ziconotide products vary in their licensed status and other characteristics which affects their suitability for intrathecal administration

Clonidine: informing intrathecal risk assessment

16 May 2025Clonidine products vary in their licensed status and other characteristics which affects their suitability for intrathecal administration

Baclofen: informing intrathecal risk assessment

7 May 2025Baclofen products vary in their licensed status and other characteristics which affects their suitability for intrathecal administration

Preparing for audits and inspections of aseptic services

10 March 2025Careful planning ensures maximum benefit for both the auditee and auditor

Registration required

Stability resources for aseptic services

7 February 2025Stability data supports extended shelf lives for aseptically prepared medicines

Shelf lives of aseptically prepared medicines in NRFit syringes

19 December 2024Provision of intrathecal and epidural injections in NRFit syringes may involve extrapolation of stability data from luer lock systems

Quality assurance for aseptic services videos

11 October 2024A series of short videos about quality assurance in aseptic services

Process risk assessments for a Contamination Control Strategy

19 March 2024Performing a Process Risk Assessment (PRA) to inform contamination control strategy for manufacturing processes within NHS units.