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Intrathecal medicines

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Cytarabine: informing intrathecal risk assessment

5 August 2025Cytarabine products vary in their licensed status and other characteristics which affects their suitability for intrathecal administration

Amikacin: informing intrathecal risk assessment

5 August 2025Amikacin products vary in their licensed status and other characteristics which affects their suitability for intrathecal administration

Hydromorphone: informing intrathecal risk assessment

8 July 2025Hydromorphone products vary in their licensed status and other characteristics which affects their suitability for intrathecal administration

Managing an intrathecal chemotherapy service

13 June 2025The intrathecal route is a high-risk route of administration. There are minimum requirements for providing intrathecal chemotherapy.

Understanding risks with intrathecal administration

13 June 2025The intrathecal route is a high-risk route of administration. Incorrect administration of medicines unsafe for this route can result in patient death.

Ziconotide: informing intrathecal risk assessment

16 May 2025Ziconotide products vary in their licensed status and other characteristics which affects their suitability for intrathecal administration

Clonidine: informing intrathecal risk assessment

16 May 2025Clonidine products vary in their licensed status and other characteristics which affects their suitability for intrathecal administration

Baclofen: informing intrathecal risk assessment

7 May 2025Baclofen products vary in their licensed status and other characteristics which affects their suitability for intrathecal administration

Shelf lives of aseptically prepared medicines in NRFit syringes

19 December 2024Provision of intrathecal and epidural injections in NRFit syringes may involve extrapolation of stability data from luer lock systems

Intrathecal administration

All our advice on using intrathecal medicines safely.