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Costing Clinical Trials of ATIMPs using the NIHR iCT - Advice for Pharmacy Sites

12 July 2022Guidance to support and promote consistent pharmacy costing for commercial clinical trials involving ATIMPs.

Using warfarin with proton pump inhibitors (PPIs)

17 June 2022PPIs may enhance warfarin anticoagulation. Patients on warfarin require counselling when starting on a PPI and INR monitored appropriately.

Using angiotensin-II receptor antagonists during breastfeeding

11 May 2023Very limited data suggest breastmilk levels are likely to be low, but other medicine classes are preferred. Recommendations apply to full term, healthy infants.

Using solid oral dosage form antibiotics in children

7 December 2022Crushing or dispersing whole solid dosage forms or opening capsules is an "off-label" use. This includes use for Group A streptococcal infections.

Using ACE inhibitors during breastfeeding

28 March 2023Enalapril is the angiotensin converting enzyme (ACE) inhibitor of choice during breastfeeding. Recommendations apply to full term and healthy infants only.

Using the Medication Safety Update effectively

15 December 2022Effective use provides assurance that an organisation is aware of the most critical medication safety related information, and acts on this to improve safety

Practice support for the Medication Safety Officer (MSO)

15 December 2022An infrastructure of support opportunities exists that MSOs should utilise to deliver their role most effectively

Conducting a medication incident investigation

15 December 2022Practical guidance to support those undertaking medication incident investigations

Communication opportunities to improve medication safety

15 December 2022Effective communication allows for timely responses to new and emerging medication risks and the sharing of potential safety solutions.

Using calcium-channel blockers during breastfeeding

2 June 2023Nifedipine and verapamil are the calcium-channel blockers of choice during breastfeeding. Recommendations apply to full term and healthy infants only.