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Safety in Breastfeeding

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Considerations and interactions with GLP-1 receptor agonists

12 November 2025Signposting key risks and interactions of GLP-1 receptor agonists in diabetes, obesity, and weight management.

Using antipsychotics during breastfeeding

14 July 2025Quetiapine is the preferred second-generation, and haloperidol the preferred first-generation antipsychotic when breastfeeding full term, healthy infants.

Managing COVID-19 and breastfeeding

1 May 2025Continue breastfeeding during COVID-19 infection, even if dexamethasone, Paxlovid, sotrovimab or tocilzumab are required. COVID-19 vaccines can also be given.

Using antihistamines during breastfeeding

1 May 2025Guidance on continuing or initiating commonly used antihistamines whilst breastfeeding. Recommendations apply to full term and healthy infants only.

Using contrast agents during breastfeeding

11 April 2025Breastfeeding need not be withheld after commonly used amidotrizoate, barium, gadolinium or iodinated contrast agents. Applies to full term and healthy infants.

Using oral anticoagulants during breastfeeding

6 December 2024Warfarin is the preferred choice during breastfeeding; rivaroxaban or dabigatran may also be used. Recommendations apply to full term and healthy infants.

Using paracetamol during breastfeeding

11 October 2024Paracetamol is one of the analgesics of choice for treating mild to moderate pain during breastfeeding. Recommendations apply to full term and healthy infants.

Using vitamin D during breastfeeding

30 August 2024Vitamin D can be used during breastfeeding; higher doses require infant monitoring. Recommendations apply to full term, healthy infants only.

Using domperidone for low milk supply

21 June 2024Domperidone can be used to treat low milk supply. However, this is only after thorough assessment and once non-medical interventions have been tried.

Using codeine, dihydrocodeine or tramadol during breastfeeding

18 June 2024Tramadol and dihydrocodeine can be used while breastfeeding for pain control. Codeine should not be used . Advice applies to full term, healthy infants.