Switching
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Switching doxazosin XL tablets to doxazosin standard tablets
12 May 2022Doxazosin XL tablets should not routinely be prescribed. Guidance is provided on switching doxazosin XL tablets to standard release tablets.
Switching between gabapentin and pregabalin for neuropathic pain
14 January 2026An overview of possible dose equivalences, switching methods and considerations to make before switching between immediate-release gabapentinoids.
Considerations when choosing an alternative antidepressant
17 September 2024Consider the risks associated with switching an antidepressant for depression, the patient's individual circumstances and when to seek specialist advice.
Switching strategies for antidepressants
22 May 2024The choice of antidepressant switching strategy depends on the person and antidepressant. We describe the current strategies and their application.
Specific medicine switches for solid dose and liquid formulations
13 February 2026Certain medicines require additional monitoring and dose adjustments when switching between solid dose and liquid formulations.
An example oral opioid switch from morphine to oxycodone
1 April 2025An example scenario to support you when switching or advising on switching between morphine and other oral opioids in cancer and palliative care.
Trazodone to other antidepressants: switching in adults
31 May 2024Suggested methods for switching safely from trazodone to other antidepressants. Switches requiring additional specialist support are highlighted.
Establishing if a person needs to switch their antidepressant
28 March 2023Prior response, side-effects, new contraindications, and current depression symptoms may require switching antidepressants. When it is, establish shared goals.
Monitoring a person during and after antidepressant switching
17 September 2024Review people at appropriate time points; advise on what to expect and report; and beware of the possibility of withdrawal symptoms and serotonin syndrome.
Estimating dose equivalence from oral morphine to other opioids
1 April 2025Use our tool to obtain approximate dose equivalences of oral morphine to other oral opioids and help you calculate an estimated equivalent daily dose.