3 January 2025 · Most drug interactions with local anaesthetics (LA) cartridges are not clinically relevant in general dentistry. We advise on management options where needed.

31 October 2023 · When individuals taking certain medicines stop, start or re-start smoking, monitoring and dose changes may be needed.

17 February 2023 · Suggested methods for switching safely between tricyclics or to other antidepressants. Switches requiring additional specialist support are highlighted.

31 January 2023 · Imipramine and nortriptyline are the tricyclic antidepressants of choice. Recommendations apply to full term and healthy infants only.