Clozapine

Using antipsychotics during breastfeeding

14 July 2025Quetiapine is the preferred second-generation, and haloperidol the preferred first-generation antipsychotic when breastfeeding full term, healthy infants.

Managing the risks associated with patients prescribed clozapine

28 June 2024Healthcare professionals in non-specialist services managing patients prescribed clozapine should implement safe practice principles to prevent potential harms.

Clinical considerations for patients prescribed clozapine

28 June 2024Healthcare professionals in all settings who interact with patients prescribed clozapine should be aware of clinical considerations related to its use.

Managing specific interactions with smoking

31 October 2023When individuals taking certain medicines stop, start or re-start smoking, monitoring and dose changes may be needed.

Clozapine use in adults with swallowing difficulties

31 May 2023Guidance on clozapine administration including crushing tablets, importance of not missing doses and practical considerations regarding switching formulations

Managing constipation in people taking clozapine

14 October 2022Constipation in people taking clozapine can be fatal. Guidance on preventing and managing constipation in these individuals is described.