Esomeprazole

PPI suggestions for adults with swallowing difficulties

14 June 2024A range of proton pump inhibitor (PPI) formulations are suitable for adults with swallowing difficulties.

Treating heartburn and dyspepsia during breastfeeding

5 March 2024Antacids, alginates, H2-receptor antagonists or proton pump inhibitors can be used during breastfeeding. Recommendations are for full term and healthy infants.

Managing interactions with methotrexate

28 December 2023Guidance on frequently asked questions on medicine interactions with low dose methotrexate.

Using clopidogrel with proton pump inhibitors (PPIs)

22 May 2023Avoid the combined use of clopidogrel with omeprazole or esomeprazole due to a significant interaction. Other PPIs are considered safe with clopidogrel.

Using bisphosphonates with proton pump inhibitors (PPIs)

4 April 2023Although no interaction between bisphosphonates and PPIs is documented, the increased risk of fractures when given together should be reviewed and managed

Using warfarin with proton pump inhibitors (PPIs)

17 June 2022PPIs may enhance warfarin anticoagulation. Patients on warfarin require counselling when starting on a PPI and INR monitored appropriately.