Shortage of Adalat (nifedipine) products

Bayer has announced that it is to permanently discontinue supply of immediate release nifedipine (5mg and 10mg) for which they are the only supplier.  There…

Safety in Lactation: Drugs for peripheral vascular disease

Additional information relating to breastfeeding To be used in conjunction with individual drug entries for specific information and guidance. Pentoxifylline is the preferred choice during…

Safety in Lactation: Drugs for hypertension

Additional information relating to breastfeeding To be used in conjunction with individual drug entries for specific information and guidance. Many of the drugs covered by…

What are the reported incidences of ankle oedema with different calcium channel blockers?

The potential to cause ankle oedema appears to exist for all calcium channel blocking agents (CCBs), and is caused by increasing capillary pressure leading to…

How should ankle oedema caused by calcium channel blockers be treated?

Ankle oedema is a common, often troublesome adverse effect for patients who are receiving calcium channel blocker (CCB) therapy, and may affect compliance. It is…

How effective are topical calcium-channel blockers for anal fissure?

Topical diltiazem 2% is at least as effective as topical GTN, with short-term healing rates between 68% and 80%. Nifedipine 0.2% to 0.5% is also…