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Safety in Lactation: Antidepressants

21 October 2020Additional information relating to breastfeeding To be used in conjunction with individual drug entries for specific information and guidance. Monamine-oxidase inhibitors (MAOIs) Due to the…

What is serotonin syndrome and which medicines cause it?

22 May 2020This Medicines Q&A outlines the causes and symptoms of serotonin syndrome and provides examples of medicines with the potential to cause serotonin syndrome.  

Is there a lactose-free antidepressant?

24 September 2019This Medicine Q&A lists currently available lactose-free antidepressant preparations. There is a lactose-free preparation available for all antidepressants except for clomipramine, doxepin, isocarboxazid, moclobemide, nortriptyline…

How do you switch between monoamine oxidase inhibitors and SSRI, tricyclic or related antidepressants?

9 September 2019This updated Medicines Q&A provides advice on the risks and suggested strategies for switching between monoamine oxidase inhibitors (MAOIs) and selective serotonin reuptake inhibitors (SSRI),…

Shortage of phenelzine 15mg tablets (Nardil™)

12 July 2019Kyowa Kirin are the sole supplier of phenelzine tablets in the UK. They are out of stock due to manufacturing issues. Phenelzine tends to only…

If antidepressant-induced hyponatraemia has been diagnosed, how should the depression be treated?

10 June 2019This Medicines Q&A evaluates the evidence available on the management of depression in patients with antidepressant-induced hyponatraemia. Summary Most antidepressants are associated with hyponatraemia, with…

What is the most appropriate antidepressant to use in people with epilepsy?

29 January 2019NICE recommend that non-pharmacological interventions such as CBT should be considered in people presenting with depression, in addition to the use of antidepressants. With respect…