Switching between liquid and tablet/capsule formulations - Which medicines require extra care?

For a small number of medicines, there are differences in equivalent doses of oral formulations of the same medicine. This Q&A considers which medicines may…

How should medicines be dosed in children who are obese?

Obesity results in physiological changes that can affect the volume of distribution and the clearance of drugs. The extent of these changes is variable and…

How can we minimise the risks to patients when using intravenous phenytoin in status epilepticus (SE)?

Intravenous phenytoin is one of a number of treatments that can be used to manage status epilepticus (SE); this is a condition where a convulsive…

Suggestions for Therapeutic Drug Monitoring in Adults in Primary Care

This document is intended to support local discussions on how to monitor commonly prescribed high risk medicines in primary care.  Comments have been included as…

Can antiepileptics (anticonvulsants) increase the risk of osteoporosis?

This updated Medicines Q&A evaluates the evidence available on the risk of osteoporosis in patients with epilepsy taking antiepileptic drugs.

Safety in Lactation: Drugs used in status epilepticus

Choice of treatment will be influenced by the clinical situation. The evidence for these drugs in breastfeeding is based on their longer-term use rather than…