In the main, bisphosphonates are not metabolized and are excreted unchanged in urine. There are concerns about using them in chronic kidney disease, end-stage renal…
There appears to be a link between bisphosphonate use and an increased risk of serious inflammatory ocular disorder such as uveitis and scleritis. The absolute…
This updated Medicines Q&A evaluates the published evidence examining the gastric safety of bisphosphonates for the treatment of osteoporosis. Alendronate should be the first choice…
Drugs used exclusively for postmenopausal osteoporosis have not been included. Bisphosphonates have very poor oral bioavailability in fasting adults, which is decreased even further in…