Safety in Lactation: Drugs affecting bone metabolism

Can oral bisphosphonates be given to people with renal impairment to treat osteoporosis?

In the main, bisphosphonates are not metabolised and are excreted unchanged in urine. Oral bisphosphonates are licensed for the primary and secondary prevention of osteoporotic…

NICE Bites: Osteoporosis

Please go to NICE to check for any recent updates to this guideline. NICE Bites is a monthly prescribing bulletin published by North West Medicines…

Is there an interaction between bisphosphonates and proton pump inhibitors?

This updated Medicines Q&A evaluates the evidence for an interaction between bisphosphonates and proton pump inhibitors.  

What are the risks of ocular adverse effects with bisphosphonate treatment?

There appears to be a link between bisphosphonate use and an increased risk of serious inflammatory ocular disorder such as uveitis and scleritis. The absolute…

Do gastric adverse events influence the choice of bisphosphonate for the treatment of osteoporosis?

This updated Medicines Q&A evaluates the published evidence examining the gastric safety of bisphosphonates for the treatment of osteoporosis. Alendronate should be the first choice…