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Gastrointestinal disorders

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Treating nausea during breastfeeding

26 March 2024Some anti-emetics can be used with caution during breastfeeding, depending on the clinical situation. Recommendations apply to full term, healthy infants.

Good governance when implementing ustekinumab biosimilar

2 August 2024Governance should consider processes for approval, procurement and supply, prescribing and administration, monitoring, and pharmacovigilance.

Preparing to use ustekinumab biosimilar

16 July 2024Introducing biosimilar ustekinumab needs planning. Work with the multidisciplinary team to ensure familiarity with the area and develop an implementation plan.

The licence and supporting evidence for ustekinumab biosimilars

2 August 2024Ustekinumab biosimilars (Pyzchiva, Steqeyma, Uzpruvo, Wezenla) are licensed. Learn about indications, formulations, supporting evidence and differences.

Using and prescribing thiamine in alcohol dependence

6 June 2024Intramuscular and intravenous thiamine can be used to prevent complications of alcohol dependence such as Wernicke’s encephalopathy.

Specific advice for using medicines following bariatric surgery

31 March 2022There is some evidence on the effect of bariatric surgery (gastric bypass) on specific medicines which may inform prescribing decisions for those patients.

Using loperamide in high output stoma or short bowel syndrome

7 November 2024This guidance explores the dosing and monitoring advice when using high dose loperamide to reduce high stoma output or in short bowel syndrome in adults.

Considerations for using medicines following bariatric surgery

30 May 2025Guidance on the physiological changes after bariatric surgery that can affect the pharmacokinetics of medicines and supplements.

Prescribing and using thiamine to prevent refeeding syndrome

2 May 2024Intravenous thiamine for prevention of refeeding syndrome should be reserved for those with intestinal failure where the oral or enteral route is unavailable.

Choosing a prokinetic medicine for impaired gastrointestinal motility

23 May 2025Prokinetics improve gastrointestinal motility. We advise on suitable prokinetic options, including dose and safety considerations.