Mental health and illness
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Choosing an antidepressant for people with epilepsy
26 March 2026Selective serotonin reuptake inhibitors (SSRIs) are the preferred antidepressant in people with epilepsy. We give considerations when selecting antidepressants.
Using antipsychotics during breastfeeding
14 July 2025Quetiapine is the preferred second-generation, and haloperidol the preferred first-generation antipsychotic when breastfeeding full term, healthy infants.
Oral benzodiazepines and choosing equivalent doses
2 July 2025Equivalent doses of oral benzodiazepines to diazepam are not exact. Consider these factors before switching.
Choosing an antidepressant for people with coronary heart disease
29 April 2025Sertraline is the first-line option in people with coronary heart disease. Alternatives include fluoxetine, paroxetine and mirtazapine.
SSRI suggestions for adults with swallowing difficulties
27 April 2026A range of selective serotonin reuptake inhibitor (SSRI) formulations are suitable for adults with swallowing difficulties.
Switching strategies for antidepressants
22 May 2024The choice of antidepressant switching strategy depends on the person and antidepressant. We describe the current strategies and their application.
Using benzodiazepines during breastfeeding
15 February 2024Lorazepam and oxazepam are the preferred benzodiazepines during breast feeding, if clinically appropriate. Recommendations apply to full term, healthy infants.
Addressing inappropriate use of antidepressants for depression and anxiety
20 January 2026Deprescribing antidepressants involves safely reducing and withdrawing them. An introduction; signposting to current resources; and SPS resources coming soon.
Prescribing and switching between modified-release methylphenidate
28 August 2025Modified-release methylphenidate capsules and tablets differ. Ensure patients receive appropriate treatment, particularly during periods of supply disruption.
Using certain antidepressants during breastfeeding
17 November 2023Duloxetine, mirtazapine, trazodone or venlafaxine can be used with caution but other options are preferred. Recommendations apply to full term, healthy infants.