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Using intramuscular injections in people on oral anticoagulants

20 September 2023Advice on risks related to use of small volume (less than 3mL) intramuscular (IM) injections in people on oral anticoagulants (for example, DOACs, warfarin)

Using written instructions for seasonal ‘flu vaccination

25 August 2021Advice on using written instructions for the administration of 'flu vaccinations to healthcare staff.

Safety in Lactation: Vaccines and antisera

21 September 2020Although vaccines and toxoids (diphtheria and tetanus) are considered to be compatible with breastfeeding, their use should be limited to those situations where there is…
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Refrigerated Storage

Fluenz TetraAstraZeneca

AstraZeneca
Fluenz Tetra
Nasal Spray Suspension

THIS ADVICE APPLIES FOR 2023/2024 INFLUENZA SEASON ONLY
In the event of an inadvertent temperature excursion the following data may be used:
The vaccine may be removed from the refrigerator once for a maximum period of 12 hours at a temperature not above 25°C. Stability data indicates the vaccine components are stable for 12 hours when stored at temperatures from 8°C to 25°C. At the end of this period, Fluenz Tetra should be used immediately or discarded.
Please also refer to the manufacturer’s product literature for recommended storage information at https://www.medicines.org.uk

21 August 2023
London MI Service

Influvac sub-unit TetraViatris (Formerly Mylan)

Viatris (Formerly Mylan)
Influvac sub-unit Tetra
Suspension for injection in pre-filled syringe

THIS ADVICE APPLIES FOR 2023/2024 INFLUENZA SEASON ONLY
Contact Viatris in all cases where a deviation from the recommended storage conditions has occurred. Refer to the electronic medicines compendium (eMC) at https://www.medicines.org.uk for company contact details and product literature.

21 August 2023
London MI Service

Quadrivalent Influenza vaccineSanofi

Sanofi
Quadrivalent Influenza vaccine
Suspension for injection in pre-filled syringe

THIS ADVICE APPLIES FOR 2023/2024 INFLUENZA SEASON ONLY
Contact Sanofi in all cases where a deviation from the recommended storage conditions has occurred. Refer to the electronic medicines compendium (eMC) at https://www.medicines.org.uk for company contact details.

4 September 2023
London MI Service

Adjuvanted quadrivalent influenza vaccineSeqirus

Seqirus
Adjuvanted quadrivalent influenza vaccine
Suspension for injection in pre-filled syringe

THIS ADVICE APPLIES FOR 2023/2024 INFLUENZA SEASON ONLY
Contact Seqirus in all cases where a deviation from the recommended storage conditions has occurred. Refer to the electronic medicines compendium (eMC) at https://www.medicines.org.uk for company contact details.

16 August 2023
London MI Service

SupemtekSanofi

Sanofi
Supemtek
Solution for injection in pre-filled syringe

THIS ADVICE APPLIES FOR 2023/2024 INFLUENZA SEASON ONLY
Contact Sanofi in all cases where a deviation from the recommended storage conditions has occurred. Refer to the electronic medicines compendium (eMC) at https://www.medicines.org.uk for company contact details.

4 September 2023
London MI Service

Cell-based quadrivalent influenza vaccineSeqirus

Seqirus
Cell-based quadrivalent influenza vaccine
Suspension for injection in pre-filled syringe

THIS ADVICE APPLIES FOR 2023/2024 INFLUENZA SEASON ONLY
Contact Seqirus in all cases where a deviation from the recommended storage conditions has occurred. Refer to the electronic medicines compendium (eMC) at https://www.medicines.org.uk for company contact details.

16 August 2023
London MI Service

Lactation Safety Information

Yes
Inactivated (intramuscular or intradermal) or live attenuated (intranasal) vaccines
Live (attenuated) virus in the intranasal vaccine has been adapted to cold in order to replicate in the nasal passage. Survival highly unlikely at breast milk temperatures.
15 October 2018