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What steroid supplementation is required for a patient with primary adrenal insufficiency undergoing a dental procedure?

5 December 2019This Medicines Q&A gives guidance on dental procedures for which steroid supplementation may be required in patients with primary adrenal insufficiency and gives advice on…

Using bisphosphonates with proton pump inhibitors (PPIs)

4 April 2023Although no interaction between bisphosphonates and PPIs is documented, the increased risk of fractures when given together should be reviewed and managed

Using oral or parenteral corticosteroids during breastfeeding

17 July 2023Corticosteroids can be used during breastfeeding. Use the lowest dose and duration possible. Recommendations apply to full term, healthy infants only.

Using strong opioid analgesics during breastfeeding

26 May 2023Morphine is the strong opioid analgesic of choice for treating pain in breastfeeding. Recommendations apply to full term and healthy infants only.

Using warfarin with proton pump inhibitors (PPIs)

17 June 2022PPIs may enhance warfarin anticoagulation. Patients on warfarin require counselling when starting on a PPI and INR monitored appropriately.

Using angiotensin-II receptor antagonists during breastfeeding

11 May 2023Very limited data suggest breastmilk levels are likely to be low, but other medicine classes are preferred. Recommendations apply to full term, healthy infants.

Using ACE inhibitors during breastfeeding

28 March 2023Enalapril is the angiotensin converting enzyme (ACE) inhibitor of choice during breastfeeding. Recommendations apply to full term and healthy infants only.

Using calcium-channel blockers during breastfeeding

2 June 2023Nifedipine and verapamil are the calcium-channel blockers of choice during breastfeeding. Recommendations apply to full term and healthy infants only.

Specific medicine switches for solid dose and liquid formulations

13 September 2023Certain medicines require additional monitoring and dose adjustments when switching between solid dose and liquid formulations.

Using oseltamivir and zanamivir during breastfeeding

12 October 2023Oseltamivir and zanamivir can be used during breastfeeding when clinically indicated. Recommendations apply to full term, healthy infants only.