Cardiovascular system disorders
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Using angiotensin-II receptor antagonists during breastfeeding
11 May 2023Very limited data suggest breastmilk levels are likely to be low, but other medicine classes are preferred. Recommendations apply to full term, healthy infants.
Using ACE inhibitors during breastfeeding
28 March 2023Enalapril is the angiotensin converting enzyme (ACE) inhibitor of choice during breastfeeding. Recommendations apply to full term and healthy infants only.
Using calcium-channel blockers during breastfeeding
2 June 2023Nifedipine and verapamil are the calcium-channel blockers of choice during breastfeeding. Recommendations apply to full term and healthy infants only.
Primary care discussions: Heart failure
20 August 2024A practical discussion between two pharmacists with an interest in heart failure about identifying heart failure and optimising treatment in primary care.
Anticoagulant suggestions for adults with swallowing difficulties
13 June 2024A range of oral anticoagulant formulations are suitable for adults with swallowing difficulties.
Managing peripheral oedema caused by calcium channel blockers
26 September 2022All calcium channel blockers may cause peripheral oedema. There are different treatment options and the incidence can be affected by different factors.
Using lipid-lowering medicines during breastfeeding
21 April 2023Rosuvastatin, pravastatin and atorvastatin are preferred; simvastatin and ezetimibe can also be used. Recommendations apply to full term and healthy infants.
Using clopidogrel with proton pump inhibitors (PPIs)
22 May 2023Avoid the combined use of clopidogrel with omeprazole or esomeprazole due to a significant interaction. Other PPIs are considered safe with clopidogrel.
Using heparins during breastfeeding
19 January 2024Low molecular weight heparin and unfractionated heparin can be used during breastfeeding. Recommendations apply to full term, healthy infants only.
ARB suggestions for adults with swallowing difficulties
20 June 2024A range of angiotensin II receptor antagonists (angiotensin receptor blockers, ARB) formulations are suitable for adults with swallowing difficulties.