Licensed medicines in suitable formulations
Warfarin 1mg/1ml oral suspension
Available as a licensed preparation. It does not require fridge storage and has an expiry of 28 days once opened.
Apixaban (Eliquis) tablets
Film-coated but are licensed to be crushed and dispersed in water, glucose 5%, apple juice or apple puree.
Film-coated but are licensed to be crushed and mixed with water or apple sauce.
Rivaroxaban (Xarelto) tablets
Film-coated but are licensed to be crushed and mixed with water or apple puree. Crushed 15mg and 20mg strengths should be immediately followed by food.
Rivaroxaban granules for oral suspension
After reconstitution, the suspension has an expiry of 14 days. It does not require fridge storage.
Licensed medicines used in an unlicensed manner
Can be crushed and/or dispersed in water or crushed and given with soft food.
Apixaban, edoxaban and rivaroxaban tablets
Can be crushed and given with soft food. (They are licensed to be given with apple puree/apple sauce.)
Dabigatran capsules must not be opened; bioavailability of the capsule contents may be increased by 75% when taken without the shell.
In view of the licensed options available, special-order preparations are unlikely to be required.