Choosing the correct dose of an anticoagulant is important to ensure that the patient receives the benefits in terms of reduction of thrombo-embolic events whilst…
This article considers the risk of interactions between NOACs and antidepressants. · Non-vitamin K antagonist oral anticoagulants (NOACs) appear to have fewer clinically significant drug…
This Medicines Q&A discusses the potential risks associated with the administration of small volume IM injections to patients taking oral anticoagulants. It has been partially…
The Oxford Academic Health Science Network (AHSN), together with Buckinghamshire Healthcare NHS Trust is currently establishing a new model of service delivery for the initiation…
NICE guidance on atrial fibrillation (AF) recommends that patients on anticoagulation with warfarin should have time in therapeutic range (TTR) assessed. Patients with TTR <65%…
This document is intended to support local discussions on how to monitor commonly prescribed high risk medicines in primary care. Comments have been included as…
Additional information relating to breastfeeding To be used in conjunction with individual drug entries for specific information and guidance. Oral anticoagulants The coumarin anticoagulants, warfarin…
NOACs offer convenient fixed dosing without need for routine coagulation monitoring and they have predictable pharmacokinetics, fewer interactions and quicker onset (and offset) of action…