Patient Group Directions

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Patient Group Directions

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Unlicensed medicines and use of PGDs

2 June 2025This page explains why PGDs are not a legal mechanism for the administration or supply of unlicensed medicines.

Using medicines at more than one location under a single PGD

5 January 2026A single Patient Group Direction (PGD) can be used to supply or administer medicines in more than one location. PGDs do not need to relate to specific premises.

Off label medicine use under a Patient Group Direction

2 June 2025This article explains the legislation and guidance on the use of PGDs when a medicine is to be used outside its licence ('off-label').

Patient Specific Directions (PSD)

5 January 2026This article describes Patient Specific Directions and the requirements for their writing and use

Including more than one medicine in a Patient Group Direction

18 June 2024This article summarises the considerations required if more than one medicine is included within a single PGD.

Sodium chloride 0.9% in multi injector devices

4 September 2025SPS PGD template for administering sodium chloride 0.9% intravenously for imaging investigations and procedures by registered Radiographers.

Considerations for developing national PGD and protocol templates

2 October 2025Decisions to develop PGD templates under the national Medicines Governance Do Once Programme depend on a variety of factors and advice on exclusions is given.

Omeprazole for use within antenatal and maternity services

22 December 2025SPS protocol templates for the supply and administration of omeprazole for caesarean section by registered midwives.

Gadopiclenol contrast agent

4 September 2025SPS PGD template for administering gadopiclenol intravenously for imaging investigations and procedures by registered Radiographers.

Intravenous hyoscine butylbromide

10 September 2025SPS PGD template for administering intravenous hyoscine butylbromide for imaging investigations by registered Radiographers.