Switching
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Moclobemide to other antidepressants: switching in adults
17 February 2023Suggested methods for switching safely from moclobemide to other antidepressants. Switches requiring additional specialist support are highlighted.
Trazodone to other antidepressants: switching in adults
17 February 2023Suggested methods for switching safely from trazodone to other antidepressants. Switches requiring additional specialist support are highlighted.
Vortioxetine to other antidepressants: switching in adults
17 February 2023Suggested methods for switching safely from vortioxetine to other antidepressants. Switches requiring additional specialist support are highlighted.
SNRIs to other antidepressants: switching in adults
17 February 2023Suggested methods for switching safely between SNRIs or to other antidepressants. Switches requiring additional specialist support are highlighted.
Agomelatine to other antidepressants: switching in adults
17 February 2023Suggested methods for switching safely from agomelatine to other antidepressants. Switches requiring additional specialist support are highlighted.
Mirtazapine to other antidepressants: switching in adults
17 February 2023Suggested methods for switching safely from mirtazapine to other antidepressants. Switches requiring additional specialist support are highlighted.
Considerations when choosing an alternative antidepressant
17 February 2023Consider the risks associated with switching an antidepressant for depression, the patient's individual circumstances and when to seek specialist advice.
Monitoring a person during and after antidepressant switching
17 February 2023Review people at appropriate time points; advise on what to expect and report; and beware of the possibility of withdrawal symptoms and serotonin syndrome.
Establishing if a person needs to switch their antidepressant
17 February 2023Prior response, side-effects, new contraindications, and current depression symptoms may require switching antidepressants. When it is, establish shared goals.
Planning and agreeing an antidepressant switching strategy
17 February 2023Guidance on planning and implementing the antidepressant switch after the need and choice of antidepressant have been decided.